LOS ANGELES—A systematic review conducted at UCLA found evidence to support the potential role of vitamins A, C, E and B3 in modifying the photoaging process (J Am Acad Dermatol. Feb. 26, 2010). They examined evidence supporting the use of vitamins in oral and topical formulations. Researchers said, “With the rise of the cosmeceutical industry, numerous formulations have surfaced with claims of reducing the clinical manifestations of photoaging. Many of these products capitalize on the positive connection the public makes with vitamins, especially with respect to their antioxidant capabilities. An impressive amount of basic science and clinical research has been conducted in both an attempt to discover novel strategies for preventing detrimental sun damage and to validate the addition of vitamins to skin care products. As dermatologists, it will be essential to provide our patients with substantiated counseling regarding the efficacy of commercial assertions.” The researchers did not the study was limited as a result of possible unpublished data or additional studies that may have been overlooked in their review.