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GliSODin® Keeps UV Rays at Bay

09/13/2007

PARIS—A vegetarian form of superoxide dismutase (SOD, as GliSODin®, from P.L. Thomas) demonstrated significant reduction in oxidative stress (sun burn) in a model using ultraviolet (UV) radiationinduced skin changes. Phototypes II endured a longer light exposure to create the skin burn after supplementation, compared to placebo. In the double blind, placebo-controlled study, UV skin burn (actinic erythema) was induced on the inner-forearms of 49 healthy subjects before supplementation with GliSODin (http://www.glisodin.org/) or placebo, and then once weekly over a four-week period with daily supplementation. The color of the skin was measured by chromometry; inflammation was assessed by videocapillaroscopy (which calculates the congestion of small blood vessels). The redness caused by the UV skin burn decreased more quickly in the GliSODin group. Regeneration of capillaries in the skin—a measure of recovery and reduction of inflammation—was higher in the GliSODin group compared to placebo. The study, published April 2007 in the European Journal of Dermatology (17, 2), was conducted by researchers at the Cutanees Engineering and Research Laboratory, Besancon, France.

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