RAMAT-GAN, Israel—IBR introduced IBR-DORMIN® Narcissus tazetta bulb extract for sunless tanning applications. It is a natural, aqueous extract from Narcissus bulbs in dormancy that are able to slow cell proliferation, thereby slowing skin turn over rates to maintain a sunless tan longer. The rate of proliferation in the basal layer of the skin is one of the factors that determines the rate of cell migration to the outer skin layers and overall skin turnover rate. Slowing down the cell proliferation rate in the basal layer will affect and slow-down the cells from reaching the surface. Thus, the removal of cells from the outer layer of the skin, the stratum corneum, is slower.
According to the American Academy of Dermatology (ADA) the most effective products available are sunless- or self-tanning lotions that contain dihydroxyacetone (DHA) as the active ingredient. DHA is a colorless sugar that interacts with the dead cells located in the stratum corneum of the epidermis. As the sugar interacts with the dead skin cell, a color change occurs. This change usually lasts approximately five to seven days from the initial application.
A test was designed by the company to compare the longevity of sunless tanning on the skin after application of cream containing IBR-DORMIN with commercial alpha hydroxy acid (AHA) containing products. The study results showed that with twice daily application of IBR-DORMIN containing cream, sunless tanning last longer, compared to base line and AHAs cream.
The IBR-DORMIN® being able to slowdown cell proliferation, may be able to slowdown the turnover of the skin and thereby maintain sunless tanning, longer.