var disqus_url = 'http://www.insidecosmeceuticals.com/news/2010/12/essential-oil-olive-oil-formulation-shows-wound-h.aspx';

Essential Oil, Olive Oil Formulation Shows Wound Healing Effect

Comments
Print

ANKARA, Turkey—A formulation derived from essential oils, olive oil and botanicals showed remarkable wound healing activity in a recent Turkish study (J Ethnopharmacol. 2010 Dec 3). Researchers developed a new ointment formulation to provide more efficient wound healing activity containing: olive oil extract of flowering aerial parts of Hypericum perforatum L. (St. John’s wort), olive oil, an equivalent mixture of Origanum majorana L. (marjoram) and Origanum minutiflorum Schwrd. et Davis essential oils (Origani aetheroleum), Salvia triloba L. essential oil.

For the evaluation of wound healing potential of this formulation (HPP crème mit Rotöl ointment) in vivo wound healing experimental models were employed on rats and mice and the efficiency was comparatively assessed against a reference ointment Madecassol®. Tissue sections were also evaluated histopathologically. Furthermore, the wound healing activity of each component was also investigated individually to determine the improvement in the healing capacity of the formulation.

The ointments of HPP crème mit Rotöl and Hypericum perforatum L. showed the highest activities on both wound models when compared to reference ointment Madecassol, while the other ingredients did not show any remarkable wound healing effect. However, the efficacy of the formulation was remarkably higher than the Hypericum L. ointment alone, which was also confirmed by histopathological evaluation. On the other hand, the formulation did not reduce elastase activity in vitro, but inhibited the collagenase activity. HPP crème mit Rotöl also exerted bactericidal and candicidal activities. To be acting on the different stages of wound healing process could be considered as a beneficial effect of the formulation for the treatment of wounds.

 

/**/ var loc = window.location.pathname;var nt=String(Math.random()).substr(2,10);document.write ('');
/**/
Comments
//window.disqus_no_style = true; (function() { var SHORTNAME = 'insidecosmeceuticals'; // Your website's shortname on Disqus var dsq = document.createElement('gascript'); dsq.type = 'text/javagascript'; dsq.async = true; dsq.src = 'http://disqus.com/forums/' + SHORTNAME + '/embed.js'; (document.getElementsByTagName('head')[0] || document.getElementsByTagName('body')[0]).appendChild(dsq); })();
/**/
 
//= 0) { query += 'url' + i + '=' + encodeURIComponent(links[i].href) + '&'; } } document.write(''); })(); //]]> /* var pageTracker = _gat._getTracker("UA-624328-41"); pageTracker._setDomainName("auto"); pageTracker._trackPageview(); /*]]>*/