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Avocado Protects UV-Induced Skin Damage

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ISRAEL—Results from a recent study determined polyhydroxylated fatty alcohols (PFAs) can play an important role as a photo-protective agent in UV-induced skin damage (Arch Dermatol Res. 2011 May;303(4):299). Exposing skin to UV radiation contributes to photoaging and to the development of skin cancer by DNA lesions and triggering inflammatory and other harmful cellular cascades. The present study tested the ability of unique lipid molecules, PFAs extracted from avocado, to reduce UVB-induced damage and inflammation in skin. Introducing PFAs to keratinocytes prior to their exposure to UVB exerted a protective effect, increasing cell viability, decreasing the secretion of IL-6 and PGE2, and enhancing DNA repair. In human skin explants, treating with PFA reduced significantly UV-induced cellular damage.

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